Table 3. Related Substance Groups.
| Related Substance Group | Referred FGE of EFSA |
|---|---|
| Branched-chain aliphatic saturated aldehydes, carboxylic acids and related esters of primary alcohols and branched-chain carboxylic acids | FGE.01Rev210) |
| Branched- and straight-chain aliphatic saturated primary alcohols and related esters of primary alcohols and straight-chain carboxylic acids and one straight-chain aldehyde | FGE.02Rev111) |
| Acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated or unsaturated aldehydes, an ester of a hemiacetal and an orthoester of formic acid | FGE.03Rev212) |
| 2-Ethylhexyl derivatives | FGE.0413) |
| Branched- and straight-chain unsaturated carboxylic acids and esters of these with aliphatic saturated alcohols | FGE.05Rev214) |
| Straight- and branched-chain aliphatic unsaturated primary alcohols, aldehydes, carboxylic acids and esters | FGE.06Rev415) |
| Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids | FGE.07Rev416) |
| Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups | FGE.08Rev517) |
| Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols and an ester of a phenol derivative | FGE.09Rev518) |
| Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones | FGE.10Rev319) |
| Aliphatic dialcohols, diketones, and hydroxyketones | FGE.11Rev320) |
| Primary saturated or unsaturated alicyclic alcohol, aldehyde, acid, and esters | FGE.12Rev521) |
| Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms | FGE.13Rev222) |
| Phenethyl alcohol, aldehyde, acetals, carboxylic acid and related esters | FGE.14Rev223) |
| Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives | FGE.15Rev224) |
| Aromatic ketones | FGE.16Rev225) |
| Pyrazine derivatives | FGE.17Rev326) |
| Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters | FGE.18Rev327) |
| Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters | FGE.20Rev428) |
| Thiazoles, thiophenes, thiazoline and thienyl derivatives | FGE.21Rev529) |
| Ring-substituted phenolic substances | FGE.22Rev130) |
| Aliphatic, alicyclic and aromatic ethers including anisole derivatives | FGE.23Rev431) |
| Pyridine, pyrrole, indole and quinoline derivatives | FGE.24Rev232) |
| Aliphatic hydrocarbons | FGE.25Rev333) |
| Amino acids | FGE. 2634) |
| One aromatic lactone | FGE.2735) |
| Vinylbenzene | FGE.2936) |
| 4-Prop-1-enylphenol and
2-methoxy-4-(prop-1-enyl)phenyl 3- methylbutyrate |
FGE.30Rev137) |
| One Epoxide | FGE.3138) |
| Flavonoids (Flavanones and dihydrochalcones) | FGE.3239) |
| Six Tetrahydrofuran Derivatives | FGE.3340) |
| One tetrahydroquinoline derivative | FGE.3441) |
| Three quinine salts | FGE.3542) |
| Two triterpene glycosides | FGE.3643) |
| 3-Butenyl isothiocyanate | FGE3844) |
| An aromatic derivative of 2-hydroxy-propionamide | FGE.4045) |
| Ion containing organic substances | FGE.4246) |
| Thujyl alcohol | FGE.4347) |
| cis-2-Heptyl-cyclopropanecarboxylic Acid | FGE.4448) |
| One tertiary amine | FGE.4549) |
| Ammonia and three ammonium salts | FGE.46Rev150) |
| Bi- and tricyclic secondary alcohols, ketones and related esters | FGE.47Rev151) |
| Aminoacetophenone | FGE.4852) |
| Xanthin alkaloids | FGE.4953) |
| Pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated in FGE.17Rev2 | FGE.50Rev154) |
| Alicyclic ketones and secondary alcohols and related esters evaluated by the JECFA (59th meeting) structurally related to alicyclic ketones secondary alcohols and related esters in FGE.09Rev3 | FGE.51Rev155) |
| Hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated in FGE.20 | FGE.5256) |
| Phenethyl alcohol, aldehyde, acid and related acetals and esters evaluated by JECFA (59th meeting) and structurally related to phenethyl alcohol, aldehyde, esters and related phenylacetic acid esters evaluated in FGE.14Rev1 and one phenoxyethyl ester evaluated in FGE.23Rev1 | FGE.53Rev157) |
| Benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated in FGE.20Rev1 | FGE.54Rev158) |
| Phenyl-substituted aliphatic alcohols and related aldehydes and esters evaluated by JECFA (63rd meeting) structurally related to phenethyl alcohol, aldehyde, esters and related phenylacetic acid esters evaluated in FGE.14 and aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives evaluated in FGE.15 | FGE.5559) |
| Monocyclic and alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols and an ester of a phenol carboxylic acid evaluated in FGE.09Rev1 | FGE.5660) |
| Two structurally related pulegone metabolites and one ester thereof evaluated by JECFA (55th meeting) | FGE.5761) |
| Phenol derivatives evaluated by JECFA (55th meeting) structurally related to ring substituted phenolic substances evaluated in FGE.22 | FGE.5862) |
| Aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated in FGE.23 Rev2 | FGE.59Rev163) |
| Eugenol and related hydroxyallylbenzene derivatives evaluated by JECFA (65th meeting) structurally related to ring-substituted phenolic substances evaluated in FGE.22 | FGE.6064) |
| Aliphatic acetals evaluated by JECFA (57th meeting) structurally related to acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated aldehydes and one orthoester of formic acid evaluated in FGE.03Rev1 | FGE.61Rev165) |
| Linear and branched-chain aliphatic unsaturated, unconjugated alcohols, aldehydes, acids, and related esters evaluated by JECFA (61st and 68th meeting) structurally related to branched- and straight-chain unsaturated carboxylic acids and esters of these with aliphatic saturated alcohols evaluated in FGE.05Rev2 and to straight- and branched-chain aliphatic unsaturated primary alcohols, aldehydes, carboxylic acids, and esters evaluated in FGE.06Rev1 | FGE.62Rev166) |
| Aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th and 69th meetings) structurally related to saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids evaluated in FGE.07Rev4 | FGE63Rev267) |
| Aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated in FGE.10Rev1 | FGE6468) |
| Sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated in FGE.13Rev2 | FGE.65Rev169) |
| Furfuryl Alcohol and Related Flavouring Substances Evaluated by JECFA (55th meeting) | FGE.66Rev170) |
| Furan-substituted compounds evaluated by JECFA at the 55th, 65th and 69th meetings | FGE.67Rev271) |
| Cinnamyl alcohol and related flavouring agents evaluated by JECFA (55th meeting) structurally related to aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives evaluated in FGE.15Rev1 | FGE.6872) |
| Aromatic substituted secondary alcohols, ketones and related esters evaluated by JECFA (57th meeting) structurally related to aromatic ketones from chemical group 21 evaluated in FGE.16 | FGE.6973) |
| Aliphatic, alicyclic, linear, alpha,beta-unsaturated, di- and trienals and related alcohols, acids and esters evaluated by JECFA (61st meeting) | FGE.7074) |
| Aliphatic, linear, alpha,beta-unsaturated carboxylic acids and related esters evaluated by JECFA (63rd meeting) structurally related to esters of branched- and straight-chain unsaturated carboxylic acids. Esters of these and straight-chain aliphatic saturated alcohols evaluated by in FGE.05Rev2 | FGE.7175) |
| Aliphatic, branched-chain saturated and unsaturated alcohols, aldehydes, acids, and related esters evaluated by the JECFA (61st meeting) structurally related to branched- and straight-chain unsaturated carboxylic acids, esters of these and straight-chain aliphatic saturated alcohols evaluated in FGE.05Rev2 | FGE.72Rev176) |
| Alicyclic alcohols, aldehydes, acids and related esters evaluated by JECFA (59th and 63rd meeting) structurally related to primary saturated or unsaturated alicyclic alcohols, aldehydes, acids and esters evaluated in FGE.12Rev4 | FGE.73Rev377) |
| Simple Aliphatic Sulphides and Thiols evaluated by the JECFA (53rd and 61st meeting) Structurally related to Aliphatic and Alicyclic Mono-, Di-, Tri-, and Polysulphides with or without Additional Oxygenated Functional Groups from Chemical Group 20 evaluated in FGE.08Rev5 | FGE.74Rev378) |
| Tetrahydrofuran derivatives and a furanone derivative evaluated by JECFA (63rd meeting) structurally related to tetrahydrofuran derivatives evaluated in FGE.33 | FGE.7579) |
| Sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 and miscellaneous substances from chemical group 30 evaluated in FGE.21Rev3 | FGE.76Rev180) |
| Pyridine, Pyrrole and Quinoline Derivatives evaluated by JECFA (63rd meeting) structurally related to Pyridine, Pyrrole, Indole and Quinoline Derivatives evaluated in FGE.24Rev2 | FGE.7781) |
| Aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic hydrocarbons evaluated in FGE.25Rev3 | FGE.78Rev282) |
| Amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated in FGE.26Rev1 | FGE.7983) |
| Alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by JECFA (61st meeting) structurally related to an aromatic lactone evaluated in FGE.27 | FGE.80Rev184) |
| Hydroxypropenylbenzenes evaluated by JECFA (61st meeting) structurally related to 2-methoxy-4-(prop-1-enyl)phenyl 3-methylbutyrate from chemical group 17 evaluated in FGE.30 | FGE.8185) |
| Epoxides evaluated by the JECFA (65th meeting) | FGE.82Rev186) |
| Ethyl maltol and two 6-keto-1,4-dioxane derivatives substances evaluated by JECFA (65th meeting) | FGE.83Rev187) |
| Anthranilate derivatives evaluated by JECFA (65th meeting) | FGE.8488) |
| Miscellaneous nitrogen-containing substances evaluated by JECFA (65th meeting) | FGE.8589) |
| Aliphatic and arylalkyl amines and amides evaluated by JECFA (65th meeting) | FGE.86Rev290) |
| Bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated in FGE.47Rev1 | FGE.87Rev291) |
| Phenol and Phenol Derivatives evaluated by JECFA (55th meeting) | FGE.8892) |
| Phenyl-substituted aliphatic tertiary alcohols and related aldehydes and esters evaluated by JECFA (63rd and 68th meetings) structurally related to aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters evaluated in FGE.18Rev1 | FGE.8993) |
| Aliphatic, acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances evaluated by JECFA (68th meeting) structurally related to aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters evaluated in FGE.18Rev1 | FGE.9094) |
| Simple aliphatic and aromatic sulphides and thiols evaluated by the JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated in FGE.08Rev5 | FGE.91Rev295) |
| Aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated in FGE.10Rev1 | FGE.9296) |
| Sulphur containing heterocyclic compounds evaluated by JECFA (68th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives evaluated in FGE.21Rev3 | FGE.93Rev197) |
| Aliphatic amines and amides evaluated in an addendum to the group of aliphatic and aromatic amines and amides evaluated by the JECFA (68th meeting) | FGE.94Rev298) |
| Aliphatic, linear or branched-chain saturated and unsaturated alcohols, aldehydes, acids and related esters evaluated by JECFA (69th meeting) structurally related to esters of branched- and straight-chain aliphatic saturated primary alcohols and of one secondary alcohol, and branched- and straight-chain unsaturated carboxylic acids evaluated in FGE.05Rev1 | FGE.9599) |
| 88 flavouring substances considered for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87 | FGE.96100) |
| Three ring-unsaturated delta-lactones | FGE.98101) |
| Furanone derivatives evaluated by the JECFA (63rd, 65th and 69th meetings) | FGE.99102) |