. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: Int J Tuberc Lung Dis. 2019 Sep 1;23(9):1005–1011. doi: 10.5588/ijtld.18.0626

Table 3.

Multinomial logistic regression analysis of risk factors for nephrotoxicity and ototoxicity

	RIFLE nephrotoxicity vs. no ADR		Ototoxicity vs. no ADR		Nephrotoxicity AND ototoxicity vs. no ADR
Variable	aOR	95%CI	aOR	95%CI	aOR	95%CI
Age (per 1-year increase)	1.08	1.03–1.12	1.01	0.94–1.07	1.11	1.05–1.17
Male	0.58	0.17–2.04	3.67	0.54–24.82	2.88	0.50–16.67
Tobacco use	0.24	0.08–0.75	0.26	0.06–1.18	0.20	0.05–0.80
Baseline CrCl (per 1 unit increase)	1.05	1.02–1.07	0.96	0.92–1.00	1.01	0.98–1.04
Initial injectable 1000 mg vs. 750 mg	1.27	0.24–6.77	1.30	0.15–11.18	0.29	0.04–1.97

RIFLE = Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease; aOR = adjusted odds ratio; CI = confidence interval; ADR = adverse drug reaction; CrCl = creatinine clearance.