Figure 2. Channels blocked and changes in AP/ECG measures. (A) hERG blockage induced early after depolarization (EAD). (B) Balanced blocking (hERG, the repolarizing current blocker, and Na+ or Ca++ channels, depolarizing current blockers) does not cause EAD. (C) TdP by hERG blocking. (D) The QT is prolonged without changes in the JTpeak length in this ECG. This figure has been adapted from a previous report.[16].
