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. 2018 Jun 18;26(2):73–78. doi: 10.12793/tcp.2018.26.2.73

Table 3. Geometric least-square means and geometric least-square mean ratios with 90% confidence intervals of the pharmacokinetic parameters of solifenacin for the two formulations.

Parameter Geometric least-square mean Geometric least-square mean ratio (Test/Reference)
Test (N=33) Reference (N=33) Point estimate 90% confidence intervals
AUClast (h·ng/mL) 470.48 453.42 1.0376 0.9702 – 1.1097
Cmax (ng/mL) 14.23 13.72 1.0369 0.9779 – 1.0993

Notes: Test=solifenacin tartrate 10.66 mg; Reference=solifenacin succinate 10 mg

AUClast, area under the plasma concentration-time curve to the last sampling time; Cmax, maximum plasma concentration.