Table 4. Summary of the stability results.
Donepezil concentration (ng/mL) | ||
---|---|---|
LoQC (0.3 ng/mL) | HiQC (35 ng/mL) | |
Re-injecta | 4.55 | −0.25 |
Processed sampleb | 2.25 | 1.01 |
Freeze-thawc | 1.10 | −1.20 |
Short-termd | 0 | −0.89 |
Stock short-terme | −4.26 | −1.14 |
Stock long-termf | 0 | 0.43 |
aafter three re-injections, bafter 24 h in the autosampler at 10℃, cafter three freeze-thaw cycles, dafter 20 h at room temperature, eafter 24 h at room temperature, fafter 24 days at 4℃; LoQC, low concentration of the quality control (QC) sample; HiQC: high concentration of the QC sample; Data are represented as the mean % change.