Table 2.
Guidelines | 2005 [13] | 2011 [7] | 2015 [14] | 2018[12] |
---|---|---|---|---|
First-line | AZT(d4T) + 3TC+ EFV(NVP) |
TDF + 3TC + EFV +LPV/r +RAV or ETV |
TDF(ABC) + 3TC (FTC) + EFV +LPV/r or ATV +RAL |
TDF(ABC) + 3TC (FTC) + EFV or RPV TAF + FTC + LPV/r or DRV/c +DTG, RAL Co-formulated: TAF/FTC/EVG/c ABC/3TC/DTG |
Alternatives |
AZT(d4T) + 3TC + IDV ddI + d4T + EFV(NVP) AZT + ddI + EFV(NVP) |
AZT + 3TC + NVP d4T + 3TC + NVP (Switch to AZT/ABC +3TC after 6 months) |
AZT + 3TC + EFV or NVP or RPV |
AZT + 3TC + EFV or NVP or RPV +LPV/r |