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. 2019 Jul 8;25(2):217–239. doi: 10.1007/s10147-019-01498-8

Table 5.

Clinicopathological features of dMMR endometrial cancer

Clinicopathological features
Lynch-associated

More common in juvenile and isthmus uteri

Endometrioid carcinoma is more common, but there are also clear cell carcinoma, serous carcinoma, and sarcoma

Carriers of the MSH6 pathogenic variant are recognized as having a comparatively high risk of endometrial cancer

Sporadic Low grade (well-differentiated) endometrioid carcinoma is more common