Table 5.
Clinicopathological features of dMMR endometrial cancer
Clinicopathological features | |
---|---|
Lynch-associated |
More common in juvenile and isthmus uteri Endometrioid carcinoma is more common, but there are also clear cell carcinoma, serous carcinoma, and sarcoma Carriers of the MSH6 pathogenic variant are recognized as having a comparatively high risk of endometrial cancer |
Sporadic | Low grade (well-differentiated) endometrioid carcinoma is more common |