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. 2020 Jan 23;12:335. doi: 10.3389/fnmol.2019.00335

TABLE 2.

Correlations between plasma BDNF levels and clinical data in HD patients and control subjects.

Age CAG HADS TFC MMSE MOTOR
HD
Pearson r 0.1945 −0.04949 0.0619 −0.1804 −0.09626 0.2247
95% confidence interval −0.09404 to 0.4529 −0.3310 to 0.2401 −0.2677 to 0.3786 −0.4412 to 0.1085 −0.3722 to 0.1953 −0.06263 to 0.4777
P value (two−tailed) 0.1714 0.7329 0.7081 0.2053 0.5061 0.1129
P value summary ns ns ns ns ns ns
NC
Pearson r 0.500 NA −0.094 NA NA NA
95% confidence interval 0.1142 to 0.6920 NA −0.5618 to 0.4235 NA NA NA
P value (two-tailed) 0.006 NA 0.736 NA NA NA
P value summary ∗∗ NA ns NA NA NA

NC, normal controls; HD patients included premanifest (PM) and manifest HD patients; HADS, Hospital Anxiety and Depression Scale; TFC, Total Functional Capacity; MMSE, Mini-Mental State Examination; MOTOR, the Unified Huntington’s Disease Rating Scale Motor component. Bold lettering denotes significant p values. ∗∗P = 0.006.