TABLE 3.
Correlations between salivary BDNF levels and clinical data.
| Saliva | ||||||
| Age | Age of Onset | HADS | TFC | MMSE | MOTOR | |
| HD | ||||||
| Pearson r | −0.1857 | −0.2189 | −0.05931 | −0.1844 | −0.04182 | 0.1952 |
| 95% confidence interval | −0.4635 to 0.1254 | −0.6031 to 0.2477 | −0.3762 to 0.2700 | −0.4798 to 0.1486 | −0.3654 to 0.2908 | −0.1376 to 0.4884 |
| P value (two-tailed) | 0.2391 | 0.3537 | 0.7273 | 0.2746 | 0.8087 | 0.2469 |
| P value summary | ns | ns | ns | ns | ns | ns |
| NC | ||||||
| Pearson r | 0.387 | NA | −0.210 | NA | NA | NA |
| 95% confidence interval | 0.05432 to 0.5686 | NA | −0.6066 to 0.2699 | NA | NA | NA |
| P value (two-tailed) | 0.021 | NA | 0.387 | NA | NA | NA |
| P value summary | ∗ | NA | ns | NA | NA | NA |
NC, normal controls; HD patients included premanifest (PM) and manifest HD patients; HADS, Hospital Anxiety and Depression Scale; TFC, Total Functional Capacity; MMSE, Mini-Mental State Examination; MOTOR, the Unified Huntington’s Disease Rating Scale Motor component. Bold lettering denotes significant p values. ∗P = 0.021.