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. 2020 Jan 29;10:1425. doi: 10.1038/s41598-020-58207-z

Table 3.

Unadjusted odds ratios (OR) and 95% confidence intervals (CI) by univariate and adjusted OR and CI by multivariate analyses for risk factors associated with the fatality of hypertension.

Analyses Men with hypertension
Univariate Multivariate
Variables (Risk factors) P Unadjusted
OR (95% CI)
P Adjusted
OR (95% CI)
Age (years old)
     ≦59 0.000 0.24 (0.18–0.31)
     60–74 0.000 0.55 (0.47–0.64) 0.012 1.46 (1.09–1.96)
     75–89 0.000 3.23 (2.80–3.72) 0.000 3.05 (2.3–4.06)
     ≧90 0.016 3.65 (2.57–5.17) 0.000 5.16 (3.26–8.17)
Cardiovascular diseases
     Coronary heart disease 0.000 2.09 (1.80–2.42) 0.000 2.12 (1.79–2.50)
Metabolic diseases >0.05
     Dyslipidemia >0.05
     Diabetes 0.002 1.14 (1.00-0.33) >0.05
     Obesity >0.05
Cerebrovascular diseases 0.000 1.44 (1.24–1.68) >0.05
     Cerebral infarction 0.000 1.48 (1.24–1.77) 0.000 1.59 (1.30–1.94)
Vertebrobasilar insufficiency >0.05
     Cerebral hemorrhage 0.000 2.95 (2.23–3.89) >0.05
     Acute cerebral hemorrhage 0.000 3.52 (2.57–4.83) 0.000 2.91 (1.47–5.77)
Hemorrhagic disorders 0.000 3.68 (3.01–4.51) 0.000 3.13 (1.80–5.47)
     Other hemorrhagic disorders >0.05
     Gastrointestinal hemorrhage 0.000 4.79 (3.60–6.37) >0.05
Acute diseases 0.000 3.31 (2.86–3.83) 0.000 1.82 (1.49–2.23)
Chronic diseases 0.000 2.49 (2.17–2.87) 0.000 1.54 (1.25–1.90)
Inflammatory or infectious diseases 0.000 4.31 (3.70–5.12) >0.05
     Tuberculosis >0.05
     Pulmonary infection 0.000 6.20 (5.34–7.20) >0.05
          Pneumonia 0.000 7.33 (6.33–8.48) 0.000 6.18 (4.35–8.78)
          Tracheobronchitis >0.05
          COPD 0.000 2.05 (1.70–2.48) >0.05
Gastrointestinal diseases >0.05
     Biliary gallbladder disease >0.05
     Upper gastrointestinal disease 0.000 1.63 (1.28–2.10) >0.05
Tumor 0.000 2.38 (2.04–2.80) 0.000 3.29 (2.69–4.02)
     Lung cancer 0.000 4.47 (3.49–5.72) 0.006 1.55 (1.14–2.11)

1Multivariate represents multivariate logistic backward regression analysis, adjusting for other factors which are significant (P < 0.05) in univariate analysis.

2Age is divided into four sub-groups. In multivariate analysis, last three sub-groups are compared with the first sub-group separately and their fatality risk increase 1.46, 3.05 and 5.16 times.

3 Except for traditional risks, pneumonia and lung cancer are also significantly associated with the fatality of men with hypertension.

4 OR = odds ratio; CI = confidence interval; COPD = chronic obstructive pulmonary disease.