Table 3.

Description of the training games.

Game	Trained cognitive function(s)	Game rules and objectives
Disillusion	Cognitive flexibility	The patients are requested to insert a form in a matrix, matching it by symbol or color with another form, in light of the orientation of the target form (horizontal or vertical). This exercise trains the ability to respond to a task modifying the rule of matching on the basis of contextual information (cognitive flexibility). The more forms the patients are able to match, the higher is the score.
Tidal Treasure	Visual-spatial memory	The patients are presented with a beach where different objects appear. They have to select an object and then all objects are covered. In the subsequent screen, they are requested to select an object that is different from the previous one and so on. Each session is composed of three beaches. Patients fail when they select a stimulus that has been already chosen. The more objects the patients select, the higher is the score. This game trains visual-spatial memory.
Speed Match	Processing speed and visual-spatial memory	The patients have to indicate as quickly as possible whether a stimulus matches the last one displayed, based on the symbol presented on it. As speed performance improves, the number of trials increases, augmenting the level of difficulty. The more correct answers are given, the higher the score. This game trains processing speed and visual-spatial memory.
Lost in Migration	Selective attention	The patients are asked to indicate with the correct arrow key the direction of the central bird among a bird flock. Other birds are presented with the same or different direction from the central bird. The more correct answers are given, the higher the score. This game trains selective visual-spatial attention.
Raindrops	Arithmetic calculation	The patients are requested to solve mathematical operations contained in rain-drops. They are asked to give an answer before the raindrop falls into the sea at the bottom of the screen. They are presented with three game possibilities within each session. The more correct calculations are performed, the higher the score. This game trains arithmetic calculation.