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. 2020 Jan 23;10:9. doi: 10.3389/fonc.2020.00009

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Copyright © 2020 Liu, Zhu, Zhang, Meng, Sun, Zhang, Fan and Kang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Soluble PD-L1 measurements in study subjects. (A) sPD-L1 overexpression in the serum of patients with glioma compared with that of meningioma patients and HCs. (B) sPD-L1 levels in the CSF of patients with glioma or meningioma. (C) sPD-L1 measurements in the serum of patients with high- or low-grade glioma. (D) sPD-L1 measurements in the CSF of patients with high- or low-grade glioma. (E) sPD-L1 measurements in the serum of patients with different pathological types of glioma. (F) sPD-L1 measurements in the CSF of patients with different pathological types of glioma. For simplicity, only significant differences are shown. The red horizontal lines within the data signify the medians. Statistical significance was defined as *p < 0.05 or ***p < 0.001.