Table 1.
Baseline epidemiological and hematological markers of study populations.
| Glioma | Meningioma | HC | p | |
|---|---|---|---|---|
| n | 73 | 20 | 49 | |
| Age (years) | 39.88 ± 16.66§ | 53.30 ± 15.73# | 36.82 ± 10.78 | <0.001* |
| Sex | ||||
| Male | 46 (63.01%) | 15 (75%) | 31 (63.27%) | 0.587 |
| Female | 27 (36.99%) | 5 (25%) | 18 (36.73%) | |
| sPD-L1 (ng/mL) | 0.5594 (0–1.4235) | 0.0688 (0.0454–1.4117) | 0.1107 (0–0.5908) | <0.001* |
| Hematological markers | ||||
| WBC (109/L) | 6.69 ± 1.76# | 6.17 ± 1.67 | 5.51 ± 1.45 | 0.001* |
| Neutrophils (109/L) | 4.25 ± 1.47# | 4.08 ± 1.55# | 3.17 ± 1.02 | <0.001* |
| Lymphocytes (109/L) | 1.92 ± 0.78 | 1.63 ± 0.59 | 1.84 ± 0.49 | 0.234 |
| Monocytes (109/L) | 0.38 ± 0.13§# | 0.32 ± 0.08 | 0.31 ± 0.09 | 0.003* |
| Platelets (109/L) | 242.49 ± 62.23§ | 198.80 ± 55.84 | 222.75 ± 49.97 | 0.011* |
| Albumin (g/L) | 45.32 ± 3.03§ | 42.78 ± 5.31# | 45.92 ± 2.36 | 0.019* |
| NLR | 2.50 ± 1.22# | 2.93 ± 1.71# | 1.78 ± 0.55 | <0.001* |
| dNLR | 1.28 ± 0.11 | 1.31 ± 0.11 | 1.27 ± 0.15 | 0.688 |
| PLR | 141.93 ± 63.11 | 138.58 ± 66.56 | 131.96 ± 47.43 | 0.656 |
| PNI | 54.93 ± 5.02§ | 50.94 ± 6.90# | 55.12 ± 3.49 | 0.027* |
| AGR | 1.70 ± 0.25 | 1.61 ± 0.23 | 1.70 ± 0.23 | 0.278 |
| Tumor characteristics | ||||
| Size (cm3) | 80.00 (1.20–439.28) | 43.57 (3.75–741.66) | Na | 0.055 |
| Ki-67 (%) | 10.0 (1.0–80.0) | 5.5 (1.0–30.0) | Na | 0.018* |
| WHO grade | ||||
| I–II | 39 (53.43%) | 19 (95%) | Na | <0.001* |
| III–IV | 34 (46.57%) | 1 (5%) | Na | |
| Steroid therapya | ||||
| no | 6 (8.2%) | 2 (10%) | Na | 0.258 |
| ≤ 3 days | 16 (21.9%) | 4 (20%) | Na | |
| 3–7 days | 33 (45.2%) | 5 (25%) | Na | |
| ≥7 days | 18 (24.7%) | 9 (45%) | Na | |
Data are shown as the means ± SD, medians (range) or number (%).
An asterisk (*) indicates a significant difference.
#
P < 0.05 vs. HC.
§
P < 0.05 vs. meningioma.
a
At a dose of 10 mg dexamethasone or 40 mg methylprednisolone per day.
WBC, white blood cell count; NLR, neutrophil-to-lymphocyte ratio; dNLR, derived NLR; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index; AGR, albumin-to-globulin ratio; Na, not applicable.