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. 2020 Jan 23;10:9. doi: 10.3389/fonc.2020.00009

Table 3.

Demographic and hematological parameters between low-grade gliomas and high-grade gliomas.

LGGs HGGs P
n 39 34
Age (year) 34.72 ± 16.66 45.79 ± 14.78 0.004*
Sex (M/F) 26/13 20/14 0.489
Tumor size (cm3) 76.95 (1.20–270.0) 98.00 (18.02–439.28) 0.075
Ki-67 (%) 5.0 (1.0–15.0) 35.0 (10.0–80.0) <0.001*
sPD-L1 (ng/mL) 0.4623 ± 0.2166 0.6316 ± 0.2899 0.006*
Hematological markers
 WBC (109/L) 6.34 ± 1.57 7.09 ± 1.9 0.070
 Neutrophils (109/L) 3.76 ± 1.2 4.81 ± 1.58 0.002*
 Lymphocytes (109/L) 2.09 ± 0.87 1.73 ± 0.6 0.046*
 Monocytes (109/L) 0.35 ± 0.11 0.42 ± 0.15 0.015*
 Platelets (109/L) 233.44 ± 63.17 252.88 ± 60.4 0.185
 Albumin (g/L) 45.95 ± 3.12 44.62 ± 2.82 0.062
 NLR 2.00 ± 0.79 3.09 ± 1.37 <0.001*
 dNLR 1.24 ± 0.08 1.33 ± 0.12 <0.001*
 PLR 122.39 ± 46.45 164.34 ± 72.37 0.005*
 PNI 56.39 ± 5.48 53.26 ± 3.89 0.007*
 AGR 1.77 ± 0.24 1.63 ± 0.24 0.012*

An asterisk (*) indicates a significant difference.

NLR, neutrophil-to-lymphocyte ratio; dNLR, derived NLR; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index; AGR, albumin-to-globulin ratio.