Table 7.
Independent risk factor for unfavorable outcome in thrombolysis: the independent effect of seizures.
| Variable | mRS 0–1 (n = 67) | mRS 2–6 (n = 66) | Crude OR 95% CI | Adjusted OR 95%CI | Adjusted p |
|---|---|---|---|---|---|
| Age, mean (SD) | 65.21 (14.52) | 69.91 (10.56) | 1.03 (1.00–1.06) | 1.03 (1.01–1.06) | 0.011* |
| Systolic arterial pressure, mean (SD) | 155.40 (32.82) | 165.12 (36.33) | 1.01(1.00–1.02) | 1.00 (0.96–1.01) | 0.484 |
| NIHSS, mean (SD) | 8.26 (4.29) | 14.48 (6.68) | 1.23 (1.15–1.34) | 1.08 (1.03–1.14) | 0.001* |
| Serum glucose, mean (SD) | 127.08 (47.03) | 155.61 (74.53) | 1.01 (1.00–1.01) | 1.00 (0.99–1.00) | 0.464 |
| Hemorrhagic transformation | 05 (5.7%) | 17 (25.8%) | 5.69 (1.98–16.39) | 2.33 (1.11–4.76) | 0.024* |
| Seizure | 06 (6.9%) | 15 (22.7%) | 3.97 (1.45–10.90) | 3.07 (1.22–7.75) | 0.018* |
| Cortical involvement | 63 (72.4%) | 54 (81.8%) | 1.71 (0.78–3.75) | 1.51 (0.73–3.14) | 0.266 |
| Large cortical area (ASPECTS ≤ 7) | 09 (11.3%) | 27 (40.9%) | 6.00 (2.57–13.99) | 2.04 (1.04–3.84) | 0.036* |
| Hypertension | 69 (79.3%) | 60 (90.9%) | 2.61 (0.97–7.00) | 0.58 (0.24–1.43) | 0.239 |
| Diabetes mellitus | 15 (17.2%) | 21 (31.8%) | 2.24 (1.05–4.79) | 0.74 (0.34–1.60) | 0.444 |
Statistically significant differences are highlighted in bold.
*
Indicate the values are statistically significant.