Table 3.
MIC values of S. aureus Sa9 and S. epidermidis F12 before (Control) and after (Treated) exposure to sub-lethal concentrations of different recombinant phage proteins.
| Strain | Assay | MIC (μM)a | |||
|---|---|---|---|---|---|
| LysRODI | LysA72 | CHAPSH3b | Lysostaphin | ||
| S. aureus Sa9 | Control | 0.57 | 1.47 | 0.33 | 0.43 |
| Treatedb | 0.49 ± 0.11 | 1.39 ± 0.24 | 0.39 ± 0.16 | >27.6 | |
| S. epidermidis LO5081 | Control | 1.14 | 2.94 ± 0.09 | 0.33 | 1.73 |
| Treatedb | 1.17 ± 0.06 | 2.48 ± 0.11 | 0.32 ± 0.01 | >27.6 | |
a
Minimum inhibitory concentration (MIC) expressed as μM.
b
MIC values after 10 rounds of exposure to protein followed by five additional rounds without protein.
Data represent the mean ± standard deviation of three independent biological repeats.