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. 2020 Jan 30;10:1847. doi: 10.1038/s41598-020-58751-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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GSIs block cellular migration (A,B) Control DMSO or GSI treated hLEC (A) at 72 hrs and HUVEC (B) at 24 hrs post-scratch. (C,D) Migration from the time of scratch (T = 0) for hLEC (C) and HUVEC (D) was measured. Quantitative data are represented as mean ± SEM. n = 4 for HUVEC and n = 3 for hLEC. Significance was determined by 2-tailed, type 2 Student’s t test, *P < 0.05, **P < 0.01. Scale bar, 200 μM.