Fig. 7.

Interactions among the laterality of dACC's functional connectivity, sex and age. T-value maps of the three-way interaction derived from the flexible factor analysis (see in Section 2) are rendered onto the Conte69_32k surfaces for (A) the superior dACC ipsilateral functional connectivity and (C) the inferior dACC contralateral functional connectivity. The maps displayed for multiple views of the ipsilateral hemisphere in Conte69_32k space: A, anterior; P, posterior; D, dorsal; V, ventral. Black curves indicate the boundaries between the seven neural networks. The locations of the superior and inferior dACC seeds are labeled as a green circle on the surfaces. The colorbar indicates different directions of the interaction. Scatter bar plots are displayed in (B) for an intuitive illustration on the three-way interaction in the region cluster as shown in (A), and in (D) for an intuitive illustration on the three-way interaction in the region cluster as shown in (C). The laterality index is quantified with LL-RR and LR-RL adjusted for head motion and global mean connectivity, respectively. Dashed curves indicate the 95% confidence intervals of the linear regression of the connectivity laterality on age.