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. 2019 Dec;7(24):797. doi: 10.21037/atm.2019.12.65

Table 7. Correlation among mRNA m6A% and the mRNA expressions of m6A modulators.

Partial correlations METTL3 METTL14 ALKBH FTO YTHDF1 YTHDF2 YTHDF3 m6A (%)
METTL3
   Partial correlation coefficient
   P value
METTL14
   Partial correlation coefficient 0.694
   P value 0.000
ALKBH
   Partial correlation coefficient 0.205 –0.084
   P value 0.360 0.710
FTO
   Partial correlation coefficient –0.338 –0.288 –0.191
   P value 0.124 0.194 0.394
YTHDF1
   Partial correlation coefficient 0.959 0.672 0.138 -0.395
   P value 0.000 0.001 0.539 0.068
YTHDF2
   Partial correlation coefficient 0.927 0.679 0.433 –0.297 0.840
   P value 0.000 0.001 0.044 0.179 0.000
YTHDF3
   Partial correlation coefficient 0.960 0.793 0.062 –0.296 0.905 0.913
   P value 0.000 0.000 0.785 0.181 0.000 0.000
m6A (%)
   Partial correlation coefficient 0.483 0.489 –0.119 –0.150 0.541 0.479 0.559
   P value 0.023 0.021 0.597 0.504 0.009 0.024 0.007

Controlled with age, gender, and smoking. mRNA, messenger RNA; m6A, N6-methyladenosine.