Table S2. The power calculation for the detected normalized intensity difference of candidate genes.
| Gene symbol | Non-hypoxemic | Hypoxemic | Mean difference | Alpha (significance level) |
Beta | Power (1-beta) | |||
|---|---|---|---|---|---|---|---|---|---|
| N | Normalized intensity (mean ± SD) | N | Normalized intensity (mean ± SD) | ||||||
| NLRP3 | 6 | 7.649±0.714 | 9 | 9.25±1.157 | 1.601 | 0.05 | 0.065 | 0.935 | |
| PSMA5 | 6 | 12.14±0.823 | 9 | 13.67±0.902 | 1.53 | 0.05 | 0.058 | 0.942 | |
| CLEC4D | 6 | 9.278±1.606 | 9 | 11.76±1.707 | 2.518 | 0.05 | 0.135 | 0.865 | |
| SOS1 | 6 | 6.216±1.43 | 9 | 7.976±1.039 | 1.76 | 0.05 | 0.223 | 0.777 | |
| CD300A | 6 | 9.462±1.354 | 9 | 10.91±0.7057 | 1.448 | 0.05 | 0.293 | 0.706 | |
| ELF1 | 6 | 9.278±1.077 | 9 | 11.05±0.9506 | 1.772 | 0.05 | 0.077 | 0.923 | |
| PRKD2 | 6 | 7.868±1.311 | 9 | 9.487±0.9846 | 1.619 | 0.05 | 0.225 | 0.775 | |
| STAT3 | 6 | 8.687±0.950 | 9 | 10.05±0.673 | 1.363 | 0.05 | 0.121 | 0.879 | |
| PSMA2 | 6 | 10.18±1.062 | 9 | 11.82±0.986 | 1.64 | 0.05 | 0.116 | 0.883 | |
The power calculation for the detected normalized intensity difference of candidate genes between groups with the present sample size was performed by Power Analysis and Sample Size (PASS) software (PASS 2008. NCSS, LLC. Kaysville, Utah, USA). For the current sample size of 9 in septic group with hypoxemia and 6 in that without and the detected normalized intensity difference of candidate genes, the detailed variables were set as above. Normalized intensity values were recorded from the microarray analysis. Mean difference = Mean (Hypoxemic) - Mean (Non-hypoxemic). The Alpha value of 0.05, as a level of significance was applied for estimation. The value of beta and respective power were obtained from power analysis of a non-Inferiority test of the difference of two means by PASS.