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Cigarette smoke (CS) induces pulmonary α‐SMA up‐regulation. Immunohistochemical staining for α‐SMA showed reactivity in peribronchial region of (a) control and (b) CS‐exposed mice following 11‐month treatment. Peribronchiolar regions staining for α‐SMA are also shown in (c) control and (d) CS‐exposed mice following 11‐month treatment. Scale bars = 40 μm. Six mice for each experimental group (control and CS mice) were used
