Table 2.
HBcAg‐CE12‐CQ10 vaccination had no effect on cardiac function
| Parameter | Control (n = 8) | LN + Qβ‐CE12 (n = 5) | LN + B‐vaccine (n = 7) |
|---|---|---|---|
| HR (bpm) | 384.46 ± 12.03 | 407.38 ± 15.56 | 367.33 ± 15.38 |
| FS (%) | 46.94 ± 1.69 | 43.57 ± 1.02 | 45.37 ± 1.15 |
| EF (%) | 83.23 ± 1.53 | 80.14 ± 1.05 | 81.87 ± 1.07 |
| LVEDD (mm) | 5.15 ± 0.14 | 5.65 ± 0.17 | 5.28 ± 0.11 |
| LVESD (mm) | 2.33 ± 0.07 | 2.51 ± 0.07 | 2.42 ± 0.06 |
| LAESD (mm) | 4.65 ± 0.21 | 5.07 ± 0.13 | 4.76 ± 0.19 |
| LAEDD (mm) | 3.57 ± 0.21 | 4.01 ± 0.10 | 3.78 ± 0.20 |
| LVPWD (mm) | 1.86 ± 0.08 | 1.82 ± 0.07 | 1.91 ± 0.07 |
| IVSD (mm) | 1.77 ± 0.05 | 1.89 ± 0.08 | 1.90 ± 0.05 |
| LVAWD (mm) | 1.89 ± 0.08 | 2.00 ± 0.11 | 1.99 ± 0.06 |
| LVPWS (mm) | 2.71 ± 0.07 | 2.69 ± 0.09 | 2.83 ± 0.07 |
| IVSS (mm) | 2.48 ± 0.04 | 2.59 ± 0.07 | 2.62 ± 0.05 |
| LVAWS (mm) | 2.72 ± 0.07 | 2.78 ± 0.09 | 2.80 ± 0.06 |
Note. All data are expressed as mean ± SEM, analysed by one‐way ANOVA.
Abbreviations: B‐vaccine, bivalent HBcAg‐CE12‐CQ10 vaccine; EF, ejection fraction; FS, fractional shortening; HR, heart rate; IVSD, diastolic interventricular septum; IVSS, systolic interventricular septum; LAEDD, left atrial end‐diastolic dimension; LAESD, left atrial end‐systolic dimension; LN, L‐NAME; LVAWD, diastolic left ventricular anterior wall; LVAWS, systolic left ventricular anterior wall; LVEDD, left ventricular end‐diastolic dimension; LVESD, left ventricular end‐systolic dimension; LVPWD, diastolic left ventricular posterior wall; LVPWS, systolic left ventricular posterior wall.