Table 1. Demographic and clinicopathological characteristics of patients with gallbladder cancer between 2010 and 2014 in the SEER database.

Demographic or characteristics	All subjects (N=1,321)	Training set (N=925)	Validation set (N=396)	P value
Age at diagnosis (year)				0.409
30–50	90	64	26
50–70	625	428	197
≥70	606	433	173
Sex				0.267
Female	919	635	284
Male	402	290	112
T 8th stage				0.472
T1	159	119	40
T2	658	451	207
T3	465	328	137
T4	39	27	12
M 8th stage				0.087
M0	1,143	790	353
M1	178	135	43
N 7th stage				0.93
N0	685	480	205
N1	589	411	178
N2	47	34	13
N 8th stage				0.929
N0	684	482	202
N1	570	396	174
N2	67	47	20
LODDS system				0.415
LODDS 1	395	279	116
LODDS 2	477	331	146
LODDS 3	381	273	108
LODDS 4	68	42	26
LNRS				0.218
LNR1	783	554	229
LNR2	89	56	33
LNR3	100	76	24
LNR4	349	239	110
Grade				0.689
I	188	136	52
II	621	432	189
III	470	325	145
IV	42	32	10
Tumor size(cm)				0.094
<3	610	413	197
3–5	443	286	99
5–10	224	192	89
≥10	44	34	10
Histology				0.761
Adenomas and adenocarcinomas	1,140	800	340
Others	181	125	56
LODDS, mean [range]	−0.584 [−2.903 to 2.417]	−0.599 [−2.903 to 2.303]	−0.549 [−2.644 to 2.417]	0.532
PLNS, mean [range]	0.916 [1–40]	0.907 [1–36]	0.939 [1–40]	0.753
RLNS, mean [range]	4.028 [1–40]	4.109 [1–40]	3.838 [1–22]	0.35
LNR system, mean [range]	0.335 [0–1]	0.331 [0–1]	0.344 [0–1]	0.609

T, N, M stage come from AJCC. SEER, Surveillance, Epidemiology, and End Results; LNR, lymph node ratio; AJCC, American Joint Committee on Cancer.