Table 2. Univariate and multivariate Cox regression analyses of HPV status with DSS and OS in the cohort study and after propensity score matching.
xxx | Cohort (n=1,539) | Propensity score matching (n=258) | |||||||
---|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||||
P value | *aHR (95% CI) | P value | P value | aHR (95% CI) | P value | ||||
Non-oropharyngeal | |||||||||
DSS | 0.094 | 0.77 (0.60–1.00) | 0.051 | 0.126 | 0.71 (0.50–1.02) | 0.065 | |||
OS | 0.140 | 0.81 (0.64–1.03) | 0.090 | 0.086 | 0.74 (0.53–1.02) | 0.070 | |||
Larynx | |||||||||
DSS | 0.041 | 0.60 (0.39–0.93) | 0.022 | 0.030 | 0.52 (0.28–0.95) | 0.034 | |||
OS | 0.036 | 0.70 (0.47–1.03) | 0.070 | 0.029 | 0.59 (0.34–1.00) | 0.049 | |||
Hypopharynx | |||||||||
DSS | 0.727 | 0.72 (0.40–1.27) | 0.262 | 0.661 | 1.02 (0.34–3.06) | 0.979 | |||
OS | 0.966 | 0.81 (0.47–1.39) | 0.444 | 0.456 | 1.10 (0.39–3.07) | 0.864 | |||
Oral cavity | |||||||||
DSS | 0.881 | 1.02 (0.68–1.55) | 0.909 | 0.828 | 0.99 (0.52–1.89) | 0.978 | |||
OS | 0.686 | 1.05 (0.71–1.56) | 0.795 | 0.743 | 0.95 (0.52–1.71) | 0.856 |
*, aHR estimated from Cox models stratified by protocol. aHR, adjusted hazard ratio; DSS, disease-specific survival; OS, overall survival.