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. 2019 Dec;7(23):783. doi: 10.21037/atm.2019.11.39

Figure 1.

Figure 1

The IC50 of paclitaxel (95% CI) in the breast cancer cell lines. (A) MDA-MB-231 parental cells: 1.209 nM (0.975–1.500 nM); (B) MDA-MB-231 resistant cells: 144.90 nM (115.80–181.40 nM); (C) MDA-MB-468 parental cells: 0.936 nM (0.738–1.186 nM); (D) MDA-MB-468 resistant cells: 40.51 nM (32.37–50.70 nM). In the presence of chloroquine, the IC50 value was markedly decreased to 11.48 nM [231] and 10.35 nM [468] in the resistant cell lines and was slightly reduced in the parental cell lines. CI, confidence interval.