MATN1-AS1 regulated the MAPK signaling pathway via RELA. (A) Quantification of mRNA expression of MATN1-AS1, RELA, ERK1/2, Bcl-2, Bax, survivin, and MMP-9 after transfection with indicated constructs; (B) representative immunoblotting images of MATN1-AS1, RELA, ERK1/2, Bcl-2, Bax, survivin, and MMP-9 after transfection with the indicated constructs; (C) semi-quantification of the immunoblotting. Data are presented as the mean ± standard deviation. *, P<0.05 vs. the NC and blank groups. GBM, glioblastoma; ERK, extracellular signal-regulated kinase; Bcl-2, B-cell leukemia-lymphoma-2; Bax, Bcl-2-associated X protein; MMP, matrix metalloproteinase; NC, negative control.