Table S1. Correlation between LAG-3 expression and clinicopathological parameters.
Variables | Correlation with LAG-3, r | P |
---|---|---|
Age | 0.091 | 0.233 |
Sex | 0.012 | 0.871 |
Smoking | −0.034 | 0.648 |
Tumor location | 0.134 | 0.070 |
T stage | −0.081 | 0.277 |
N stage | 0.154 | 0.038 |
Pathologic differentiation | 0.127 | 0.087 |
Vascular invasion | −0.002 | 0.982 |
Perineural involvement | −0.068 | 0.363 |
Surgical type | −0.099 | 0.180 |
CTLA-4 | 0.261 | <0.001 |
CD8 | −0.185 | 0.012 |
LAG-3, lymphocyte activation gene-3; CTLA-4, cytotoxic T-lymphocyte-associated antigen-4; TIL, tumor-infiltrating lymphocyte.