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. 2015 Nov 5;17:19–27. doi: 10.1016/j.dcn.2015.10.008

Table 2.

Areas that showed a significant group × load interaction.

Regions where adults showed greater activation as a function of difficulty level than children
Region Hem MNI Coordinates
Cluster Size (voxels) Z value P-value
x y z
Superior Parietal Gyrus extending to Precuneus L −30 −64 46 2962 6.35 2.96 × 10−10
Superior Parietal Gyrus extending to Precuneus R 36 −60 54 2595 6.19 2.68 × 10−9
Inferior Frontal Gyrus L −48 26 18 924 5.05 3.94 × 10−4
Inferior Frontal Gyrus R 38 30 14 682 4.64 3.56 × 10−3
Cerebellum R 24 −64 −24 634 4.54 5.66 × 10−3
Middle Frontal Gyrus L −34 6 58 456 4.65 0.04
Regions where adults showed less activation as a function of difficulty level than children
Region Hem MNI Coordinates
Cluster size (Voxels) Z value p-Value
x y z
Anterior medial prefrontal cortex L −4 62 22 3155 6.49 9.62 × 10−11
Anterior cingulate/cingulate gyrus L −4 18 24 X 5.51
Anterior cingulate/cingulate gyrus R 4 14 26 X 4.69
Anterior medial prefrontal cortex R 12 68 10 X 5.05
Heschl's gyrus R 42 −20 14 1707 4.88 8.94 × 10−7
Posterior cingulate cortex L −12 −50 36 1094 4.24 9.42 × 10−5

Note: the p-value shown for each cluster represents the estimated significance as determined by the FEAT toolbox of FSL; X = peak local maximas within cluster.