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. 2020 Jan 21;10:3145. doi: 10.3389/fmicb.2019.03145

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Copyright © 2020 Chu, Zhai, Xu, Li, Li, Chen and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Continuous light resulted in impaired glucose metabolism in liver, adipose tissue, and muscle. (A) HOMA-IR. (B) HOMA-β. (C,D) The mRNA abundance of Leptin and Ir in liver tissue, respectively. (E,F) The mRNA abundance of Ir and Irs1 in adipose tissue, respectively. (G,H) The mRNA abundance of Glut4 and Leptin in muscle, respectively. N = 11/group. Values are expressed as means ± SEM. Significant differences between the two groups are indicated by asterisks (^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001).