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. 2020 Jan 21;10:3145. doi: 10.3389/fmicb.2019.03145

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Copyright © 2020 Chu, Zhai, Xu, Li, Li, Chen and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Time-dependent alterations of gut microbiota community in L/D group and L/L group. (A,B) Boxplots of α-diversity (Chao1 diversity index) among time points in the L/D and L/L groups, respectively. (C,D) PCoA plot with different relative abundances of OTUs among time points in the L/D and L/L groups, respectively. (E,F) Taxonomic compositions of bacterial communities in phylum level among time points in the two groups. C-0, C-1, C-2, C-3, C-4 indicated the clusters of samples collected at the weekly time point in the L/D group of rats, respectively. L-0, L-1, L-2, L-3, L-4 indicated the clusters of samples collected at the weekly time point in the L/L group of rats. N = 5/group. One-way ANOSIM analysis was performed to show the differences among time points. Significant differences between groups were indicated by P < 0.05.