Table 6.
Association between HW phenotype and breast cancer by logistic regression.
| All subjects(n = 595) | Premenopausal(n = 383) | Postmenopausal(n = 209) | ER+/PR+(n = 293) | ER+/PR–(n = 59) | ER–/PR–(n = 148) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
| Univariate model | ||||||||||||||||||
| WC+TG (normal = reference) | 1.66 | 1.10–2.50 | 0.016 | 1.63 | 0.95–2.82 | 0.077 | 1.72 | 0.91–3.22 | 0.09 | 2.06 | 1.29–3.27 | 0.002 | 1.70 | 0.73–4.00 | 0.222 | 1.43 | 0.76–2.67 | 0.266 |
| Multivariate modela | ||||||||||||||||||
| WC+TG (normal=reference) | 1.56 | 1.02–2.39 | 0.039 | 1.49 | 0.85–2.63 | 0.167 | 1.60 | 0.82–3.12 | 0.170 | 1.95 | 1.21–3.13 | 0.006 | 1.71 | 0.72–4.08 | 0.225 | 1.21 | 0.63–2.33 | 0.571 |
WC, waist circumference; TG, triglycerides; ER, estrogen receptor; PR, progesterone receptor.
a
Adjusted for age, number of childbirths, age at menarche, breastfeeding, smoking, alcohol use, family history of breast cancer, and contraceptive drug use.