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. 2016 Oct 6;74(6):983–1000. doi: 10.1007/s00018-016-2373-0

Fig. 3.

Fig. 3

Physiology of the failing heart. An excess load chronically imposed the heart results in failure to satisfy the metabolic requirements of end organ tissues, afflicting the patient with pulmonary edema and excess fluid and sodium retention. *RAAS renin–angiotensin–aldosterone system