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. 2019 Jul 25;117(12):2455–2470. doi: 10.1016/j.bpj.2019.07.030

Figure 1.

Figure 1

An Eyring plot illustrating the difference between a Generalized Eyring equation (Eq. 4), a Typical Eyring equation (Eq. 3), and a Q10 formulation (Eq. 9). This plot extends from −10 to 50°C to highlight the differences between the three formulations. The green shaded region marks the temperature range of interest, from 22 to 37°C. The Generalized Eyring relationship shown has [lnaGE, bGE, cGE, dGE] = [40, 1000, 3000, −70], and the Typical Eyring and Q10 relationships are the best fits to the generated Generalized Eyring relationship. Both Eyring formulations give the same straight-line dependence for ln(A/T), and even the nonlinear Q10 formulation is indistinguishable (for practical purposes) within the relevant temperature range. However, the three formulations can display very different behavior when examining the temperature dependence of the voltage-dependence parameter B. To see this figure in color, go online.