Figure 2.

A framework for quantification of myocardial microstructure. (A) A local myocardial coordinate system is defined using a 3D structure tensor. (B) The collagen network is segmented in the confocal images using a pipeline of image processing. (C) A number of ROIs are extracted with a single, connected collagen structure at the center. (D) The overall representative collagen shape and organization can be fully described in terms of eigenvalues and eigenvectors of the lumped inertia matrix (see text for details). To see this figure in color, go online.