Table 3.
Serogroup C, W and Y-specific IgG GMCs with 95% CI measured in mother samples collected prior to and 28 days post-vaccination, at delivery and 3 and 6 months post partum, cord blood and infant samples collected at 3 and 6 months of age.
| Source | Timepoint | MenC |
MenW |
MenY |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | GMC (−/+ 95%CI) | % ≥2 µg/mL (−/+ 95%CI) | n | GMC (−/+ 95%CI) | % ≥2 µg/mL (−/+ 95%CI) | n | GMC (−/+ 95%CI) | % ≥2 µg/mL (−/+ 95%CI) | ||
| Mother | Pre-vaccination | 50 | 2.79 (1.87–4.17) | 60.0 (45.2–73.6) | 50 | 1.49 (1.09–2.04) | 32.0 (19.5–46.7) | 50 | 2.49 (2.12–2.92) | 66.0 (51.2–78.8) |
| 4 weeks post-vaccination | 50 | 12.67 (9.03–17.80) | 92.0 (80.8–97.8) | 50 | 48.13 (31.86–72.71) | 92.0 (80.8–97.8) | 50 | 33.97 (23.43–49.25) | 90.0 (78.2–96.7) | |
| Infant | Cord | 48 | 6.01 (3.99–9.05) | 81.3 (67.4–91.1) | 48 | 19.30 (12.11–30.75) | 89.6 (77.3–96.5) | 48 | 14.73 (9.89–21.95) | 89.6 (77.3–96.5) |
| 3 months of age | 51 | 1.01 (0.73–1.40) | 29.4 (17.5–43.8) | 48 | 4.17 (2.83–6.16) | 62.5 (47.4–76.0) | 48 | 4.13 (3.04–5.61) | 64.6 (49.5–77.8) | |
| 6 months of age | 45 | 0.47 (0.31–0.73) | 17.8 (8.0–32.1) | 48 | 1.67 (1.18–2.38) | 41.7 (27.6–56.8) | 48 | 3.07 (2.34–4.02) | 62.5 (47.5–76.0) | |
CI, Confidence interval; GMC, Geometric mean concentration; Men, Meningococcal serogroup.