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. 2020 Jan 10;5(3):1363–1370. doi: 10.1021/acsomega.9b01962

Table 2. Antileishmanial Activity, Cytotoxic Activity, and Selectivity Index of the Leaf Essential Oils from S. phalerata.

sample IC50 (μg mL–1) CC50 (μg mL–1) selectivity index (SI)
Leishmania amazonensis (promastigote stage) vero cells ATCC CCL 81
dry essential oil >512 >512  
rainy essential oil 165.05 ± 33.26 >512 3.10
amphotericin Ba 0.29 ± 0.01 8.65b 29.8
cisplatinea   7.01 ± 0.66  
a

Positive control.

b

Nigussie et al.;21 IC50, inhibitory concentration; CC50, cytotoxic concentration.