Table 2. Antileishmanial Activity, Cytotoxic Activity, and Selectivity Index of the Leaf Essential Oils from S. phalerata.
| sample | IC50 (μg mL–1) | CC50 (μg mL–1) | selectivity index (SI) |
|---|---|---|---|
| Leishmania amazonensis (promastigote stage) | vero cells ATCC CCL 81 | ||
| dry essential oil | >512 | >512 | |
| rainy essential oil | 165.05 ± 33.26 | >512 | 3.10 |
| amphotericin Ba | 0.29 ± 0.01 | 8.65b | 29.8 |
| cisplatinea | 7.01 ± 0.66 |
Positive control.
Nigussie et al.;21 IC50, inhibitory concentration; CC50, cytotoxic concentration.