Table 2.
Multivariate logistic regression analysis exploring the association of age at diagnosis, gender, race, tumor histology, tumor size, tumor grade and N stage with the presence of brain metastasis
| Variable | Odds Ratio | 95%CI Low | 95%CI Up | P value |
|---|---|---|---|---|
| Age (decade) | 0.70 | 0.70 | 0.71 | <.001 |
| Histology | ||||
| Squamous | 1 | |||
| Adenocarcinoma | 2.93 | 2.84 | 3.01 | <.001 |
| Large | 2.46 | 2.26 | 2.68 | <.001 |
| Others | 2.42 | 2.34 | 2.50 | <.001 |
| Tumor size | ||||
| 0–3cm | 1 | |||
| 3.1–5cm | 1.60 | 1.56 | 1.65 | <.001 |
| >5cm | 1.83 | 1.78 | 1.88 | <.001 |
| Unknown | 1.37 | 1.33 | 1.41 | <.001 |
| Tumor grade | ||||
| I | 1 | |||
| II | 2.16 | 2.00 | 2.34 | <.001 |
| III | 4.13 | 3.83 | 4.45 | <.001 |
| IV | 3.97 | 3.52 | 4.47 | <.001 |
| Unknown | 5.42 | 5.04 | 5.84 | <.001 |
| N stage | ||||
| N0 | 1 | |||
| N1 | 2.00 | 1.93 | 2.08 | <.001 |
| N2 | 2.24 | 2.18 | 2.30 | <.001 |
| N3 | 2.10 | 2.03 | 2.18 | <.001 |
| Unknown | 2.13 | 2.06 | 2.21 | <.001 |