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. 2020 Jan 29;11:41. doi: 10.1186/s13287-020-1552-y

Table 1.

The comparisons of white, brown, and beige adipose tissue

Types of adipose tissue Specific gene Anatomy Lipid droplet Specific markers Function
White adipose tissue UCP1 negative Abdomen subcutis A large unilocular lipid droplet Tcf21 Lipid storage, secrete hormones and cytokines
Brown adipose tissue UCP1 positive Neck supraclavicular regions Multilocular lipid droplets Zic1 Thermogenesis secrete hormones and cytokines
Beige adipose tissue UCP1 positive WAT Multilocular lipid droplets Tbx1, Epsti1 Cd137, Tmem26 Thermogenesis

WAT, white adipose tissue; UCP1, uncoupling protein 1; Tcf21, transcription factor 21; Zic1, zinc finger protein of the cerebellum 1; Tbx1, T-box 1; Epsti1, epithelial stromal interaction 1; Cd137, tumor necrosis factor receptor superfamily, member 9; Tmem26, transmembrane protein 26