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. 2020 Jan 29;15:31. doi: 10.1186/s13023-020-1297-9

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Representation of OXPHOS system in mitochondria. Energetic metabolism produces intermediates that can be used by cytochromes and be submitted to oxidation-reduction states producing electrons and in last step promoting ADP association to an inorganic phosphate resulting in ATP. Elaborated with Servier Medical Art