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. 2020 Jan 23;10:3152. doi: 10.3389/fimmu.2019.03152

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Copyright © 2020 Wepler, Preuss, Merz, Hartmann, Wachter, McCook, Vogt, Kress, Gröger, Fink, Scheuerle, Möller, Calzia, Burret, Radermacher, Tuckermann and Vettorazzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mitochondrial respiration (JO₂) in tissue from heart (A), liver (B), muscle (C), and brain (D) in GR^dim/dim and GR^+/+ mice intraperitoneal challenged with lipopolysaccharide (LPS) or vehicle (PBS). *p < 0.05 vs. GR^+/+ PBS. ^#p < 0.05 vs. GR^dim/dim PBS. Overall p-values from Kruskal–Wallis-Test are shown above accordingly. LPS = lipopolysaccharide from Escherichia coli [055:B5], 10 mg·kg⁻¹, dissolved in 10 μl·g⁻¹ phosphate buffered saline [PBS]. GR^+/+ mice challenged with PBS: n = 7–8, GR^dim/dim mice challenged with PBS: n = 4–5, GR^+/+ mice challenged with LPS: n = 3–8, GR^dim/dim mice challenged with LPS: n = 6–11. Data is presented as median (25th and 75th percentile and minimum/maximum).