Table 3. Antiviral Activity against Coxsackievirus B4 and Hepatitis A Virus HM 175 of Compounds with Viral Reduction 50% or More in Terms of CC50, IC50 (μg/μL), and SIa.
coxsackievirus
B4 |
hepatitis
A virus HM 175 |
|||||
---|---|---|---|---|---|---|
compd no. | CC50 (μg/μL) | IC50 (μg/μL) | SI | CC50 (μg/μL) | IC50 (μg/μL) | SI |
5a | 0.22 | 0.085 | 2.59 | 0.22 | 0.10 | 2.20 |
5b | 0.20 | 0.11 | 1.82 | NT | NT | |
9a | 0.22 | 0.084 | 2.62 | 0.24 | 0.078 | 3.08 |
9b | 0.22 | 0.092 | 2.39 | 0.23 | 0.086 | 2.67 |
9c | 0.17 | 0.09 | 1.89 | NT | NT | |
14b | 0.18 | 0.093 | 1.93 | 0.22 | 0.010 | 2.20 |
14c | 0.23 | 0.091 | 2.53 | 0.23 | 0.010 | 2.30 |
14g | 0.19 | 0.082 | 2.32 | 0.23 | 0.081 | 2.84 |
14h | 0.19 | 0.074 | 2.57 | 0.20 | 0.074 | 2.70 |
NT = not tested.