Table 3. Comparison of the Neuropsychologic Profiles in All Cohortsa.
| Domain | Group Differences | TSC vs HC | FTD vs HC | TSC vs FTD | Omnibus Model | ||||
|---|---|---|---|---|---|---|---|---|---|
| β | P Value | β | P Value | β | P Value | Fdf | Model P Value | ||
| Executive | (TSC = FTD) >HC | 1.15 | .002 | 1.44 | <.001 | –0.3 | .39b | 9.854,43 | <.001 |
| Language | (TSC = FTD) >HC | 1.71 | .01 | 2.89 | <.001 | –1.17 | .07b | 6.614,43 | <.001 |
| Spatial | FTD ≠ TSC ≠ HC | 0.07 | .88 | 0.11 | .78 | –0.04 | .93b | 0.684,45 | .61 |
| Memory | TSC >FTD | NA | NA | NA | NA | –1.87 | .04 | 4.433,26 | .01 |
Abbreviations: FTD, frontotemporal dementia; HC, healthy control; TSC, tuberous sclerosis complex.
a
P values less than .05 were considered significant.
b
Insignificant changes in all categories when TSC was compared with FTD. Note that the data used to calculate the information for the HC and FTD for neuropsychological testing were different from the participants who completed the TAND checklist.