Radar plots of adjusted Expanded Prostate Cancer Index Composite functional domain scores. The center of each figure represents worst function (score of 0) and the outermost line represents best function (score of 100). For the sexual function domain, the minimum clinically important difference in score is 10-12; urinary incontinence domain, 6-9; urinary irritative domain, 5-7; and bowel and hormonal function domains, 4-6. The regression models were adjusted for baseline domain score, age, race/ethnicity, comorbidities, cancer characteristics, physical function, social support, depression, medical decision-making style, and accrual site.