Direct and indirect comparisons should be read from left to right. Hazard ratios for comparisons are in the cell in common between the column-defining and row-defining treatment. For progression-free survival, a hazard ratio of less than 1 favors row-defining treatment. For overall survival, a hazard ratio of less than 1 favors column-defining treatment. Bev indicates bevacizumab; CTX, continuing induction regimen; FP, fluoropyrimidine; MTC, maintenance; and OBS, observation.