Table 2. Baseline Characteristics.
| Characteristic | Patients, No. (%) | P Valuea | |
|---|---|---|---|
| Bridge to Transplant/Bridge to Candidacy (n = 396) | Destination Therapy (n = 624) | ||
| Age | |||
| Mean (SD), y | 55 (12) | 63 (12) | <.001 |
| Median (range), y | 58 (18-73) | 65 (22-84) | |
| Male | 310 (78.3) | 513 (82.2) | .12 |
| Race | |||
| White | 266 (67.2) | 437 (70.0) | .37 |
| Black or African American | 113 (28.5) | 151 (24.2) | |
| Asian | 2 (0.5) | 9 (1.4) | |
| Native Hawaiian or Pacific Islander | 1 (0.3) | 3 (0.5) | |
| Other | 14 (3.5) | 24 (3.8) | |
| Ischemic cause of heart failure | 155 (39.1) | 297 (47.6) | .01 |
| History of atrial fibrillation | 158 (39.9) | 292 (46.8) | .03 |
| Intravenous inotropic agents | 327(82.6) | 534 (85.6) | .22 |
| Coronary bypass surgery | 48 (12.1) | 165 (26.4) | <.001 |
| Intra-aortic balloon pump | 63 (15.9) | 76 (12.2) | .09 |
| Serum creatinine, mean (SD), mg/dL | 1.3 (0.4) | 1.4 (0.4) | <.001 |
| Estimated glomerular filtration rate, mean (SD), mL/min/1.73 m2 | 64.9 (24.6) | 57.7 (21.2) | <.001 |
| Albumin, mean (SD), g/dL | 3.7 (0.5) | 3.6 (0.5) | <.001 |
| Blood urea nitrogen, mean (SD), mg/dL | 25.9 (12.5) | 29.2 (13.6) | <.001 |
| INTERMACS profile | |||
| 1 | 15 (3.8) | 12 (1.9) | .15 |
| 2 | 112 (28.3) | 187 (30.0) | |
| 3 | 198 (50.0) | 325 (52.1) | |
| 4 | 59 (14.9) | 89 (14.3) | |
| 5-7 | 11 (2.8) | 7 (1.1) | |
| Not provided | 1 (0.3) | 4 (0.6) | |
Abbreviation: INTERMACS, Interagency Registry for Mechanically Assisted Circulatory Support.
SI conversion factors: To convert albumin to g/L, multiply by 10; blood urea nitrogen to mmol/L, multiply by 0.357; serum creatinine to μmol/L, multiply by 88.4.
a
Data were compared between groups using unpaired t tests or Fisher exact tests and χ2 tests, as appropriate.