Table 1. Baseline Patient Data in a Study of the Effect of Rocuronium vs Succinylcholine on Out-of-Hospital Endotracheal Intubation Success.
| Characteristic | No. (%) | |
|---|---|---|
| Rocuronium (n = 610) | Succinylcholine (n = 616) | |
| Age, mean (SD), y | 57.2 (18.7) | 54.6 (19.1) |
| Sex | ||
| Men | 370 (60.7) | 366 (59.3) |
| Women | 240 (39.3) | 250 (40.7) |
| BMI, mean (SD) | 25.5 (5.4) | 25.8 (5.1) |
| Medical history | ||
| Hypertension | 208 (35.9) (n = 580) | 178 (30.1) (n = 592) |
| Smoking | 151 (26.4) (n = 572) | 127 (21.9) (n = 580) |
| Alcoholism | 112 (19.4) (n = 576) | 107 (18.2) (n = 589) |
| Cancer | 55 (9.4) (n = 582) | 42 (7.1) (n = 593) |
| Coronary heart disease | 51 (8.8) (n = 580) | 42 (7.1) (n = 592) |
| Chronic obstructive pulmonary disease | 50 (8.6) (n = 578) | 34 (5.7) (n = 592) |
| Heart failure | 50 (8.6) (n = 579) | 29 (4.9) (n = 591) |
| Chronic kidney failure | 19 (3.3) (n = 580) | 20 (3.4) (n = 591) |
| Reason for intubationa | ||
| Coma due to neurological disease | 313 (51.3) | 304 (49.4) |
| Coma due to self-poisoning | 107 (17.5) | 124 (20.1) |
| Acute respiratory failure | 101 (16.6) | 71 (11.5) |
| Trauma | 51 (8.4) | 52 (8.4) |
| Shock | 8 (1.3) | 9 (1.5) |
| Other | 30 (4.9) | 56 (9.1) |
| Characteristics at enrollment | ||
| Glasgow Coma Scale score, median (IQR)b | 6.0 (3.0-8.0) | 6.0 (3.0-8.0) |
| Heart rate, mean (SD), beats/min | 99.4 (28.4) | 95.6 (27.2) |
| Respiratory rate, mean (SD), breaths/min | 21.4 (9.7) | 21.1 (9.5) |
| Arterial systolic pressure, mm Hg | ||
| <90 | 47 (7.7) | 37 (6.0) |
| >140 | 258 (42.3) | 227 (36.9) |
| Arterial diastolic pressure, mm Hg | ||
| <50 | 43 (7.0) | 35 (5.7) |
| >90 | 193 (31.6) | 168 (27.3) |
| Peripheral oxygen saturation, mean (SD), % | 95.4 (6.8) | 95.4 (7.5) |
| Sedation given for intubation | ||
| Etomidate | 536 (87.9) | 543 (88.1) |
| Total dose, median (IQR), mg | 30 (20-40) | 30 (20-40) |
| Ketamine | 38 (6.2) (n = 609) | 34 (5.5) |
| Total dose, median (IQR), mg | 150 (67-190) | 200 (125-250) |
| Pentothal | 21 (3.4) (n = 609) | 19 (3.1) (n = 615) |
| Total dose, median (IQR), mg | 350 (200-400) | 325 (250-400) |
| Propofol | 21 (3.4) | 21 (3.4) |
| Total dose, median (IQR), mg | 60 (40-150) | 150 (80-160) |
| Combined administration, No. | 6 | 1 |
| Patient position during intubation | ||
| Lying on a stretcher | 324 (53.1) | 307 (49.8) |
| Lying on the ground | 161 (26.4) | 187 (30.4) |
| Lying on a bed | 112 (18.4) | 110 (17.9) |
| Other | 13 (2.1) | 12 (1.9) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); IQR, interquartile range.
a
Coded by the emergency physician.
b
Range, 3 (deep coma) to 15 (normal consciousness).