Table. Univariate and Multivariate Analyses of Risk Factors for Metastasis.
| Characteristic | No. of Cases | HR (95% CI) | P Value |
|---|---|---|---|
| Univariate Analysis | |||
| Age, y | |||
| <60 | 23 | 1 [Reference] | .17 |
| ≥60 | 20 | 0.49 (0.17-1.4) | |
| Sex | |||
| Male | 21 | 1 [Reference] | .14 |
| Female | 22 | 0.46 (0.16-1.33) | |
| Diameter, mm | |||
| ≤15 | 17 | 1 [Reference] | .31 |
| >15 | 26 | 1.72 (0.6-4.95) | |
| Thickness, mm | |||
| ≤10 | 22 | 1 [Reference] | .43 |
| >10 | 21 | 1.49 (0.55-4) | |
| Tumor location | |||
| On the equator | 28 | 1 [Reference] | .07 |
| Anterior to the equator | 4 | 2.55 (0.69-9.36) | |
| Posterior to the equator | 10 | 0.36 (0.08-1.62) | |
| Retinal detachment | |||
| No | 4 | 1 [Reference] | .06 |
| Yes | 39 | 0.32 (0.09-1.11) | |
| Histologic type | |||
| Spindle cells | 10 | 1 [Reference] | >.99 |
| Epithelioid or mixed | 13 | 1 (0.28-3.55) | |
| BAP1 locus deletion | |||
| No | 24 | 1 [Reference] | .001 |
| Yes | 19 | 5.91 (1.89-18.54) | |
| 8q Gain | |||
| No | 16 | 1 [Reference] | .007 |
| Yes | 27 | 6.02 (1.36-26.61) | |
| Multivariate Analysis | |||
| BAP1 locus deletion | |||
| No | 24 | 1 [Reference] | .001 |
| Yes | 19 | 6.65 (2.09-21.18) | |
| 8q Gain | |||
| No | 16 | 1 [Reference] | .01 |
| Yes | 27 | 6.88 (1.53-30.86) | |
Abbreviation: HR, hazard ratio.