Figure 3. Predictive Accuracy of the Polygenic Risk Score (PRS) in the Coronary Artery Risk Development in Young Adults (CARDIA) Study Relative to the Clinical Risk Model That Includes Baseline and Serial Body Mass Index (BMI) Assessment.

Shown is the predicted vs observed year 25 BMI in white (A and B) and black (C and D) individuals in the PRS model and the baseline BMI model. The models are described in the Statistical Modeling subsection of the Methods section. Points above the dashed line represent individuals whose BMI increased from baseline to year 25. BMI is calculated as weight in kilograms divided by height in meters squared.