Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 1;17(2):145–152. doi: 10.7150/ijms.38371

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Biologically active BFT is necessary for enhancing colonic tumorigenesis in the AOM/DSS model. BALB/c mice were infected with WT-ETBF (bft-2), rETBF (bft-2) or rNTBF (bft-2 H352Y) and subjected to the standard ETBF/AOM/DSS (2%) protocol for 12 weeks. +E2, WT-ETBF (bft-2) + AOM/DSS; +rE2, rETBF (bft-2) + AOM/DSS; rN2 (bft-2 H352Y) + AOM/DSS; A/D, AOM/DSS alone. (A) Representative gross macroscopic image of the colon. White arrows indicate polyps. (B) Polyp number. S, sham control. (C) Polyp size distribution. (D) Spleen weight. (E) Colon length. Each dot represents one mouse (n = 9-12 mice per group). Horizontal bar, median. *P < 0.05, **P < 0.01, ***P < 0.001. ns, no statistical significance.