Table 1.
The 100 top-ranking promoters based on combined ranking score.
| Gene | Gene symbol | Category | RNA class | Chromosome | mean.mean β value (NS) | mean.mean β value (W) | mean.mean β value diff. (W-NS) |
mean.mean. quot.log2 | comb.p.val | comb.p.adj. (FDR) | Combined rank |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ENSG00000224674 | EIF3EP2 | Pseudogene | 2 | 0.611 | 0.154 | -0.458 | -1.924 | 7.832E-16 | 3.519E-11 | 1 | |
| ENSG00000263368 | AC069366.1 | Pseudogene | antisense | 17 | 0.206 | 0.573 | 0.367 | 1.431 | 1.336E-13 | 2.001E-09 | 14 |
| ENSG00000173198 | CYSLTR1 | Protein coding | X | 0.166 | 0.520 | 0.353 | 1.580 | 1.671E-11 | 4.415E-08 | 17 | |
| ENSG00000266228 | MIR3611 | RNA gene | miRNA | 10 | 0.403 | 0.128 | -0.275 | -1.584 | 1.083E-11 | 3.744E-08 | 27 |
| ENSG00000267125 | AC012615.3 | RNA gene | 19 | 0.192 | 0.465 | 0.273 | 1.280 | 3.531E-13 | 3.410E-09 | 29 | |
| ENSG00000270808 | AC022400.4 | Pseudogene | lncRNA | 10 | 0.691 | 0.295 | -0.396 | -1.202 | 1.686E-10 | 1.756E-07 | 40 |
| ENSG00000241114 | AC008280.2 | Pseudogene | 2 | 0.383 | 0.129 | -0.254 | -1.503 | 1.876E-10 | 1.756E-07 | 47 | |
| ENSG00000272156 | AC008280.3 | RNA gene | 2 | 0.383 | 0.129 | -0.254 | -1.503 | 1.876E-10 | 1.756E-07 | 47 | |
| ENSG00000207258 | RF00019 | RNA gene | Y RNA | 1 | 0.508 | 0.192 | -0.315 | -1.356 | 6.373E-10 | 4.522E-07 | 62 |
| ENSG00000226545 | AL357552.1 | Pseudogene | 1 | 0.508 | 0.192 | -0.315 | -1.356 | 6.373E-10 | 4.522E-07 | 62 | |
| ENSG00000270002 | AC022028.2 | RNA gene | 10 | 0.458 | 0.199 | -0.259 | -1.056 | 5.656E-10 | 4.246E-07 | 70 | |
| ENSG00000227096 | HMGB3P8 | Pseudogene | 10 | 0.653 | 0.246 | -0.408 | -1.376 | 1.138E-09 | 6.141E-07 | 82 | |
| ENSG00000250532 | AC021180.1 | RNA gene | 4 | 0.621 | 0.233 | -0.388 | -1.378 | 1.576E-09 | 7.956E-07 | 89 | |
| ENSG00000254653 | AC024475.1 | RNA gene | 11 | 0.228 | 0.440 | 0.212 | 1.071 | 1.411E-10 | 1.756E-07 | 99 | |
| ENSG00000265503 | MIR1269B | RNA gene | miRNA | 17 | 0.346 | 0.141 | -0.205 | -1.239 | 1.140E-09 | 6.141E-07 | 109 |
| ENSG00000238024 | DDX39BP2 | Pseudogene | 6 | 0.326 | 0.124 | -0.202 | -1.323 | 1.391E-09 | 7.248E-07 | 113 | |
| ENSG00000273044 | AL022334.2 | RNA gene | 22 | 0.243 | 0.481 | 0.238 | 0.956 | 1.766E-10 | 1.756E-07 | 119 | |
| ENSG00000234105 | AC009468.2 | RNA gene | 7 | 0.576 | 0.307 | -0.269 | -0.961 | 3.100E-09 | 1.151E-06 | 121 | |
| ENSG00000188373 | C10orf99 | Protein coding | 10 | 0.400 | 0.202 | -0.198 | -0.982 | 5.786E-10 | 4.262E-07 | 124 | |
| ENSG00000271597 | AC112230.1 | Pseudogene | lncRNA | 2 | 0.306 | 0.594 | 0.287 | 0.933 | 3.019E-09 | 1.151E-06 | 136 |
| ENSG00000271265 | AL355297.3 | RNA gene | lncRNA | 6 | 0.347 | 0.667 | 0.320 | 0.924 | 1.317E-11 | 3.856E-08 | 145 |
| ENSG00000244286 | ITGB5-AS1 | RNA gene | ncRNA | 3 | 0.202 | 0.393 | 0.190 | 1.223 | 8.912E-12 | 3.640E-08 | 152 |
| ENSG00000226403 | AL392089.1 | RNA gene | 9 | 0.080 | 0.269 | 0.189 | 1.633 | 1.086E-12 | 6.969E-09 | 154 | |
| ENSG00000234936 | AC010883.1 | RNA gene | 2 | 0.288 | 0.498 | 0.210 | 0.909 | 2.020E-11 | 4.908E-08 | 158 | |
| ENSG00000203527 | Z99756.1 | RNA gene | ncRNA | 22 | 0.385 | 0.198 | -0.187 | -0.906 | 5.290E-09 | 1.674E-06 | 161 |
| ENSG00000242147 | AL365356.5 | RNA gene | ncRNA | 10 | 0.334 | 0.148 | -0.186 | -1.263 | 3.506E-11 | 7.161E-08 | 166 |
| ENSG00000270781 | AC091133.5 | Pseudogene | 17 | 0.416 | 0.219 | -0.197 | -0.896 | 4.980E-10 | 3.925E-07 | 170 | |
| ENSG00000250282 | AC002401.2 | RNA gene | 17 | 0.225 | 0.443 | 0.217 | 0.894 | 3.488E-09 | 1.234E-06 | 174 | |
| ENSG00000255158 | AC131934.1 | RNA gene | 11 | 0.299 | 0.590 | 0.291 | 0.977 | 1.016E-08 | 2.625E-06 | 174 | |
| ENSG00000232486 | AL592437.2 | Pseudogene | 9 | 0.666 | 0.354 | -0.312 | -0.892 | 1.930E-09 | 8.758E-07 | 175 | |
| ENSG00000262067 | AC120057.1 | Pseudogene | lncRNA | 17 | 0.505 | 0.171 | -0.333 | -1.505 | 1.139E-08 | 2.816E-06 | 181 |
| ENSG00000266258 | LINC01909 | RNA gene | ncRNA | 18 | 0.629 | 0.299 | -0.330 | -1.048 | 1.479E-08 | 3.408E-06 | 195 |
| ENSG00000257496 | AC025031.1 | RNA gene | 12 | 0.217 | 0.397 | 0.180 | 0.982 | 1.649E-08 | 3.703E-06 | 200 | |
| ENSG00000185479 | KRT6B | Protein-coding | 12 | 0.340 | 0.166 | -0.174 | -1.045 | 7.004E-11 | 1.124E-07 | 216 | |
| ENSG00000270255 | AC009884.2 | Pseudogene | 8 | 0.279 | 0.529 | 0.250 | 0.900 | 2.221E-08 | 4.587E-06 | 217 | |
| ENSG00000167751 | KLK2 | Protein coding | 19 | 0.328 | 0.136 | -0.192 | -1.214 | 2.772E-08 | 5.463E-06 | 227 | |
| ENSG00000268518 | AC020909.2 | RNA gene | 19 | 0.432 | 0.238 | -0.194 | -0.839 | 2.897E-11 | 6.197E-08 | 229 | |
| ENSG00000243795 | LINC02044 | RNA gene | ncRNA | 3 | 0.387 | 0.663 | 0.276 | 0.825 | 1.229E-11 | 3.856E-08 | 246 |
| ENSG00000267632 | AC067852.3 | RNA gene | lncRNA | 17 | 0.402 | 0.719 | 0.316 | 0.821 | 1.561E-10 | 1.756E-07 | 254 |
| ENSG00000259265 | AC027088.3 | RNA gene | 15 | 0.362 | 0.195 | -0.167 | -0.918 | 2.209E-08 | 4.587E-06 | 260 | |
| ENSG00000264733 | MIR4718 | RNA gene | miRNA | 16 | 0.342 | 0.176 | -0.166 | -0.922 | 1.674E-09 | 8.164E-07 | 263 |
| ENSG00000253630 | AC026407.1 | Pseudogene | antisense | 5 | 0.537 | 0.301 | -0.236 | -0.815 | 1.148E-09 | 6.141E-07 | 264 |
| ENSG00000228918 | LINC01344 | RNA gene | ncRNA | 1 | 0.180 | 0.346 | 0.166 | 0.908 | 4.232E-10 | 3.475E-07 | 264 |
| ENSG00000232878 | DPYD-AS1 | RNA gene | ncRNA | 1 | 0.572 | 0.387 | -0.185 | -0.815 | 4.216E-08 | 7.523E-06 | 265 |
| ENSG00000112769 | LAMA4 | Protein coding | 6 | 0.325 | 0.512 | 0.187 | 0.810 | 3.888E-08 | 7.072E-06 | 269 | |
| ENSG00000237126 | AC073254.1 | RNA gene | 2 | 0.368 | 0.202 | -0.166 | -0.835 | 1.684E-08 | 3.745E-06 | 270 | |
| ENSG00000256746 | AC018410.1 | RNA gene | ncRNA | 11 | 0.344 | 0.536 | 0.192 | 0.807 | 2.084E-09 | 9.002E-07 | 271 |
| ENSG00000232560 | C21orf37 | RNA gene | ncRNA | 21 | 0.300 | 0.495 | 0.195 | 0.805 | 5.048E-08 | 8.338E-06 | 274 |
| ENSG00000198796 | ALPK2 | Protein coding | 18 | 0.165 | 0.329 | 0.163 | 0.924 | 1.006E-08 | 2.622E-06 | 286 | |
| ENSG00000185432 | METTL7A | Protein coding | 12 | 0.389 | 0.673 | 0.283 | 0.795 | 7.318E-13 | 5.480E-09 | 286 | |
| ENSG00000087076 | HSD17B14 | Protein coding | 19 | 0.145 | 0.346 | 0.201 | 1.168 | 5.925E-08 | 9.251E-06 | 287 | |
| ENSG00000239255 | AC007620.1 | Pseudogene | 3 | 0.347 | 0.575 | 0.227 | 1.085 | 6.353E-08 | 9.775E-06 | 292 | |
| ENSG00000230403 | LINC01066 | RNA gene | ncRNA | 13 | 0.475 | 0.302 | -0.173 | -0.902 | 8.129E-08 | 1.192E-05 | 306 |
| ENSG00000132475 | H3F3B | Protein coding | 17 | 0.173 | 0.358 | 0.184 | 1.003 | 8.349E-08 | 1.218E-05 | 308 | |
| ENSG00000258274 | AC012085.2 | RNA gene | ncRNA | 12 | 0.415 | 0.624 | 0.208 | 0.785 | 6.143E-11 | 1.062E-07 | 308 |
| ENSG00000244167 | AC005532.2 | Pseudogene | lncRNA | 7 | 0.488 | 0.281 | -0.207 | -0.775 | 4.380E-08 | 7.657E-06 | 324 |
| ENSG00000266740 | MIR4708 | RNA gene | miRNA | 14 | 0.240 | 0.416 | 0.177 | 0.771 | 4.844E-10 | 3.887E-07 | 328 |
| ENSG00000258657 | AL136018.1 | RNA gene | 14 | 0.448 | 0.234 | -0.213 | -0.946 | 1.163E-07 | 1.588E-05 | 329 | |
| ENSG00000186715 | MST1L | Protein coding | 1 | 0.300 | 0.145 | -0.156 | -1.006 | 6.774E-11 | 1.124E-07 | 335 | |
| ENSG00000253543 | AC083923.1 | Pseudogene | 8 | 0.277 | 0.121 | -0.156 | -1.127 | 6.441E-10 | 4.522E-07 | 339 | |
| ENSG00000261095 | AC136285.1 | RNA gene | ncRNA | 16 | 0.487 | 0.272 | -0.215 | -0.958 | 1.368E-07 | 1.803E-05 | 341 |
| ENSG00000213316 | LTC4S | Protein coding | 5 | 0.211 | 0.365 | 0.154 | 1.075 | 1.025E-08 | 2.631E-06 | 348 | |
| ENSG00000267299 | AC011444.3 | RNA gene | 19 | 0.141 | 0.300 | 0.159 | 0.752 | 2.936E-08 | 5.687E-06 | 352 | |
| ENSG00000234502 | FYTTD1P1 | Pseudogene | 9 | 0.361 | 0.180 | -0.182 | -0.969 | 1.678E-07 | 2.118E-05 | 356 | |
| ENSG00000265666 | RARA-AS1 | RNA gene | ncRNA | 17 | 0.189 | 0.339 | 0.151 | 0.868 | 1.088E-07 | 1.501E-05 | 370 |
| ENSG00000182264 | IZUMO1 | Protein coding | 19 | 0.308 | 0.468 | 0.160 | 0.737 | 3.157E-08 | 5.910E-06 | 376 | |
| ENSG00000254113 | AC090193.2 | RNA gene | 8 | 0.243 | 0.419 | 0.177 | 0.736 | 1.371E-08 | 3.276E-06 | 378 | |
| ENSG00000204933 | CD177P1 | Pseudogene | 19 | 0.375 | 0.607 | 0.232 | 0.733 | 2.798E-09 | 1.103E-06 | 382 | |
| ENSG00000110203 | FOLR3 | Protein coding | 11 | 0.536 | 0.357 | -0.180 | -0.746 | 1.990E-07 | 2.311E-05 | 387 | |
| ENSG00000266964 | FXYD1 | Protein coding | 19 | 0.299 | 0.452 | 0.154 | 0.731 | 3.068E-09 | 1.151E-06 | 391 | |
| ENSG00000221857 | AC020907.2 | RNA gene | 19 | 0.299 | 0.452 | 0.154 | 0.731 | 3.068E-09 | 1.151E-06 | 391 | |
| ENSG00000213417 | KRTAP2-4 | Protein coding | 17 | 0.471 | 0.309 | -0.163 | -0.855 | 2.328E-07 | 2.604E-05 | 401 | |
| ENSG00000254853 | AP004247.1 | Pseudogene | 11 | 0.247 | 0.100 | -0.147 | -1.221 | 3.631E-09 | 1.265E-06 | 410 | |
| ENSG00000283664; ENSG00000265375 | MIR4679-1; MIR4679-2 | RNA gene | miRNA | 10 | 0.353 | 0.589 | 0.236 | 0.722 | 1.858E-10 | 1.756E-07 | 410 |
| ENSG00000261257 | AP000821.1 | RNA gene | lncRNA | 11 | 0.394 | 0.543 | 0.149 | 0.746 | 2.524E-07 | 2.757E-05 | 411 |
| ENSG00000204880 | KRTAP4-8 | Protein coding | 17 | 0.356 | 0.198 | -0.158 | -0.823 | 2.945E-07 | 3.114E-05 | 425 | |
| ENSG00000215930 | MIR942 | RNA gene | miRNA | 1 | 0.410 | 0.266 | -0.144 | -0.782 | 8.361E-09 | 2.305E-06 | 427 |
| ENSG00000271680 | AC098935.2 | Pseudogene | antisense | 1 | 0.244 | 0.100 | -0.144 | -1.211 | 4.741E-08 | 7.978E-06 | 428 |
| ENSG00000258380 | AL356805.1 | RNA gene | 14 | 0.292 | 0.435 | 0.144 | 1.043 | 2.010E-08 | 4.354E-06 | 432 | |
| ENSG00000249717 | AC110760.2 | RNA gene | ncRNA | 4 | 0.480 | 0.694 | 0.213 | 0.707 | 5.817E-08 | 9.171E-06 | 436 |
| ENSG00000265462; ENSG00000266758 | MIR3680-1; MIR3680-2 | RNA gene | miRNA | 16 | 0.383 | 0.630 | 0.247 | 0.705 | 8.156E-10 | 5.161E-07 | 438 |
| ENSG00000263361 | MIR378H | RNA gene | miRNA | 5 | 0.411 | 0.268 | -0.143 | -0.731 | 7.162E-08 | 1.080E-05 | 443 |
| ENSG00000249483 | AC026726.1 | RNA gene | lncRNA | 5 | 0.114 | 0.257 | 0.142 | 0.852 | 1.524E-08 | 3.459E-06 | 446 |
| ENSG00000227735 | CYCSP5 | Pseudogene | antisense | 1 | 0.212 | 0.070 | -0.142 | -1.478 | 2.842E-09 | 1.110E-06 | 449 |
| ENSG00000267130 | AC008738.2 | RNA gene | 19 | 0.163 | 0.310 | 0.146 | 0.698 | 3.087E-08 | 5.835E-06 | 449 | |
| ENSG00000269480 | AC020913.2 | RNA gene | 19 | 0.388 | 0.226 | -0.162 | -0.755 | 4.211E-07 | 3.933E-05 | 481 | |
| ENSG00000260673 | AL034376.1 | RNA gene | 6 | 0.392 | 0.254 | -0.139 | -0.703 | 8.046E-08 | 1.187E-05 | 482 | |
| ENSG00000261392 | AC087190.2 | RNA gene | 16 | 0.735 | 0.481 | -0.255 | -0.681 | 2.657E-07 | 2.869E-05 | 488 | |
| ENSG00000196344 | ADH7 | Protein coding | 4 | 0.290 | 0.152 | -0.138 | -0.936 | 2.488E-07 | 2.740E-05 | 488 | |
| ENSG00000170454 | KRT75 | Protein coding | 12 | 0.467 | 0.293 | -0.175 | -0.729 | 4.448E-07 | 4.087E-05 | 489 | |
| ENSG00000254175 | IGLVI-42 | Pseudogene | 22 | 0.232 | 0.095 | -0.137 | -1.201 | 1.475E-10 | 1.756E-07 | 498 | |
| ENSG00000254073 | IGLVVII-41-1 | Pseudogene | 22 | 0.232 | 0.095 | -0.137 | -1.201 | 1.475E-10 | 1.756E-07 | 498 | |
| ENSG00000253947 | AC008705.1 | RNA gene | 5 | 0.393 | 0.582 | 0.189 | 0.677 | 1.507E-08 | 3.438E-06 | 498 | |
| ENSG00000275874 | PICSAR | RNA gene | ncRNA | 21 | 0.467 | 0.318 | -0.150 | -0.675 | 2.541E-07 | 2.757E-05 | 503 |
| ENSG00000233930 | KRTAP5-AS1 | RNA gene | ncRNA | 11 | 0.162 | 0.298 | 0.136 | 0.944 | 1.138E-08 | 2.816E-06 | 503 |
| ENSG00000188100 | FAM25A | Protein coding | 10 | 0.389 | 0.254 | -0.135 | -0.688 | 1.426E-07 | 1.862E-05 | 509 | |
| ENSG00000261078 | AC009118.1 | RNA gene | 16 | 0.250 | 0.115 | -0.135 | -1.008 | 2.220E-08 | 4.587E-06 | 513 | |
| ENSG00000259195 | AC021739.1 | Pseudogene | 15 | 0.284 | 0.149 | -0.134 | -0.927 | 4.219E-08 | 7.523E-06 | 519 | |
| ENSG00000260905 | AC009021.1 | RNA gene | 16 | 0.616 | 0.384 | -0.232 | -0.667 | 8.523E-08 | 1.235E-05 | 523 | |
| ENSG00000006831 | ADIPOR2 | Protein coding | 12 | 0.721 | 0.501 | -0.220 | -0.667 | 1.007E-07 | 1.410E-05 | 527 |